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Deep vein thrombosis (DVT) is characterized specifically by the presence of a thrombus, or blood clot, within a deep vein, most commonly in the legs. This condition disrupts normal blood flow and can lead to serious complications, including pulmonary embolism if the clot dislodges and travels to the lungs.

The formation of a thrombus in a deep vein typically occurs due to factors such as prolonged immobilization, certain medical conditions, or surgery, all of which can lead to stasis of blood, changes in blood vessel walls, or hypercoagulability.

In contrast, the other options describe different conditions or phenomena not specific to DVT. The presence of air in the bloodstream relates to air embolism, swelling in superficial veins pertains to superficial venous thrombosis or other circulatory issues, and increased blood clotting in arteries does not define DVT, as DVT specifically refers to clots in veins, not arteries. Understanding these distinct characteristics helps in the accurate diagnosis and management of these conditions in the clinical setting.

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