Which body system is most directly affected by deep vein thrombosis?

Deep vein thrombosis (DVT) primarily affects the circulatory system. DVT occurs when a blood clot (thrombus) forms in the deep veins, most commonly in the legs. This condition can impede normal blood flow, potentially leading to serious complications such as pulmonary embolism if the clot dislodges and travels to the lungs.

The circulatory system is responsible for the transport of blood, nutrients, gases, and waste products throughout the body. When a thrombosis occurs, particularly in the deep veins, it directly disrupts the normal flow of venous blood back to the heart. The complications associated with DVT, such as increased pressure in the veins, may also lead to swelling, pain, and even skin changes in the affected limb.

In contrast, the other body systems listed do not directly experience the primary effects of DVT. The respiratory system may be affected secondarily if a clot travels to the lungs, but it is not the system primarily impacted by the formation of a clot in the deep veins. The nervous and digestive systems are also not involved in the direct consequences of DVT.